Services

Data Analytics, Real-World Evidence & AI Driven Insights

Where complex data becomes clear, actionable strategy

Evidence Strategy & Generation
Fit-for-Purpose Data Sourcing & Feasibility
RWE Study Design & Execution
Retrospective Database Analyses
Epidemiology & Pharmacoepidemiology
Treatment Patterns & Adherence Analysis
Predictive Modeling
AI/ML & Advanced Analytics
Regulatory-Grade Evidence Generation
Publication & Dissemination Strategy
Proprietary data access

Unique expertise in the All of Us dataset

Innopiphany has unique access to the All of Us Research Program, providing insight into areas ranging from genetic data and social drivers of health to how diseases affect historically underserved and underrepresented populations — and is one of the first organizations to have experience analyzing these data.

NIH research program studying individual differences in lifestyle, socioeconomics, environment, and biology.

747,000+ national participants and still growing, with a goal of 1,000,000+ people.

Biobank repository for processing, storing, and sharing bio-samples (35M+ vials).

983 questions across 8 cross-sectional surveys, ranging from overall health and quality of life to social drivers of health.

68,000+ participants with Fitbit wearable data capturing activity, heart rate, steps, and sleep.

Healthcare provider networks totaling 10 regional medical centers, 6 FQHCs, the VA, and 165 enrollment sites.

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Patient Surveys
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EHR
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Whole-Genome Sequencing (short-read)
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SDoH Survey
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Fitbit Data (incl. sleep)

Approximate analyzable record counts available to Innopiphany within the All of Us Research Program.

Selected work

RWE & Data Analytics in Action

A sample of how Innopiphany applies the All of Us dataset, advanced analytics, and machine learning to real client challenges across therapeutic areas.

Caregiver Burden

Mapping CNS Patient Severity for Caregiver Burden

Worked with a pharmaceutical manufacturer to build a predictive model from survey data that classifies CNS patients by disease severity.

Access RWE — Obesity, MDD, AD

Access to Healthcare & Adherence

Collaborated with the University of California, Irvine to examine whether social determinants of health in the All of Us dataset impact several large indications.

CMS CED & IRA RWE Strategy

CMS Coverage with Evidence Development & IRA RWE Analysis

Supported prospective RWE study design for CMS Coverage with Evidence Development in IRA negotiations; built a Medicare-focused value story from disease-specific data.

RWE Strategy

RWE Dataset Identification

Identified fit-for-purpose RWE datasets to solve key challenges across Alzheimer’s agitation, MDD, HIV, 340B, inflammation, and rare disease.

SDoH RWE — PTSD, Narcolepsy

Impact of SDoH on Health Conditions

Partnered with manufacturers to run multivariate logistic and Cox regressions, quantifying how social drivers of health affect patient outcomes.

Predicting Undiagnosed PTSD

Predict Undiagnosed PTSD with ML

With up to 90% of PTSD undiagnosed, leverages sociodemographic, SDoH, clinical, and geographic data to identify at-risk patients.

ICER Predictive Analytics

Predictive Algorithm for ICER Risk

Sentinnel — a machine-learning algorithm built with ensemble techniques that incorporates FDA and ICER data to estimate ICER assessment likelihood.

RSV Capstone Project

Identifying RSV Hotspots in Orange County

With UC Irvine and CHOC, applied geospatial analytics, clustering, and dashboarding to visualize and monitor localized RSV burden.

Rare Nephrology Outcomes RWE

Drivers of Outcomes: Rare vs. Common Kidney Disease

Conducted descriptive analysis, logistic regression, and survival analysis to identify drivers, with a subgroup analysis on lupus nephritis.

All of Us Rapid Insight Generation

Automated Statistics & Visualization across Disease Areas

Automated functions leverage the breadth of All of Us EHR and survey data to accelerate analytic turnaround.

Comprehensive IRA Predictions

Predictive Algorithm & Dashboard for IPAY Risk

IRAdar — a dashboard and machine-learning workflow that predicts the likelihood of IPAY selection using Medicare, 10-K, FDA, and proprietary data.

Clinical Trial Diversity

Data-Driven Patient Recruitment

Developed a strategy using a composite set of databases to identify, recruit, consent, and retain new and diverse patient populations for trials.